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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   MRC2 Antibody (monoclonal) (M01)   

MRC2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant MRC2.

  • WB - MRC2 Antibody (monoclonal) (M01) AT2900a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBG0
Other Accession NM_006039
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2D7
Calculated MW 166674 Da
Additional Information
Gene ID 9902
Other Names C-type mannose receptor 2, C-type lectin domain family 13 member E, Endocytic receptor 180, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein, UPAR-associated protein, Urokinase receptor-associated protein, CD280, MRC2, CLEC13E, ENDO180, KIAA0709, UPARAP
Target/Specificity MRC2 (NP_006030, 105 a.a. ~ 214 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMRC2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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MRC2 is a recycling endocytic receptor that functions in cell motility and remodeling of the extracellular matrix by promoting cell migration and uptake of collagens for intracellular degradation (Wienke et al., 2007 [PubMed 17974964]).


Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180. Messaritou G, et al. J Cell Sci, 2009 Nov 15. PMID 19861500.Novel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variants. Wu X, et al. Cancer Prev Res (Phila), 2009 Jul. PMID 19584075.The collagen receptor Endo180 (CD280) Is expressed on basal-like breast tumor cells and promotes tumor growth in vivo. Wienke D, et al. Cancer Res, 2007 Nov 1. PMID 17974964.Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer. Sulek J, et al. J Histochem Cytochem, 2007 Apr. PMID 17189524.HIV-1 Tat interaction with cyclin T1 represses mannose receptor and the bone morphogenetic protein receptor-2 transcription. Caldwell RL, et al. Arch Biochem Biophys, 2006 May 15. PMID 16615932.

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$ 315.00
Cat# AT2900a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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