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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   MSLN Antibody (monoclonal) (M02)   

MSLN Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant MSLN.

  • WB - MSLN Antibody (monoclonal) (M02) AT2917a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • IP - MSLN Antibody (monoclonal) (M02) AT2917a
    Immunoprecipitation of MSLN transfected lysate using anti-MSLN monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with MSLN MaxPab rabbit polyclonal antibody.
  • E - MSLN Antibody (monoclonal) (M02) AT2917a
    Detection limit for recombinant GST tagged MSLN is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13421
Other Accession NM_005823
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 1A10
Calculated MW 68986 Da
Additional Information
Gene ID 10232
Other Names Mesothelin, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, Megakaryocyte-potentiating factor, MPF, Mesothelin, cleaved form, MSLN, MPF
Target/Specificity MSLN (NP_005814, 464 a.a. ~ 563 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMSLN Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.


Mesothelin (MSLN) promoter is hypomethylated in malignant mesothelioma, but its expression is not associated with methylation status of the promoter. Tan K, et al. Hum Pathol, 2010 Sep. PMID 20573372.A Large-scale genetic association study of esophageal adenocarcinoma risk. Liu CY, et al. Carcinogenesis, 2010 Jul. PMID 20453000.Mesothelin gene expression and promoter methylation/hypomethylation in gynecological tumors. Obulhasim G, et al. Eur J Gynaecol Oncol, 2010. PMID 20349783.Soluble mesothelin related peptides (SMRP) and osteopontin as protein biomarkers for malignant mesothelioma: analytical validation of ELISA based assays and characterization at mRNA and protein levels. Rai AJ, et al. Clin Chem Lab Med, 2010 Feb. PMID 20131968.Polymorphisms in the putative micro-RNA-binding sites of mesothelin gene are associated with serum levels of mesothelin-related protein. Cristaudo A, et al. Occup Environ Med, 2010 Apr. PMID 19858537.

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$ 315.00
Cat# AT2917a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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