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>   home   >   Products   >   Primary Antibodies   >   MTHFD1L Antibody (monoclonal) (M01)   

MTHFD1L Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant MTHFD1L.

  • WB - MTHFD1L Antibody (monoclonal) (M01) AT2927a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - MTHFD1L Antibody (monoclonal) (M01) AT2927a
    MTHFD1L monoclonal antibody (M01), clone 1E8 Western Blot analysis of MTHFD1L expression in PC-12 ( (Cat # AT2927a )
  • E - MTHFD1L Antibody (monoclonal) (M01) AT2927a
    Detection limit for recombinant GST tagged MTHFD1L is 0.3 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6UB35
Other Accession NM_015440
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1E9
Calculated MW 105790 Da
Additional Information
Gene ID 25902
Other Names Monofunctional C1-tetrahydrofolate synthase, mitochondrial, Formyltetrahydrofolate synthetase, MTHFD1L, FTHFSDC1
Target/Specificity MTHFD1L (NP_056255, 801 a.a. ~ 899 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMTHFD1L Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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One-carbon substituted forms of tetrahydrofolate (THF) are involved in the de novo synthesis of purines and thymidylate and support cellular methylation reactions through the regeneration of methionine from homocysteine. MTHFD1L is an enzyme involved in THF synthesis in mitochondria (Christensen et al., 2005 [PubMed 15611115]).


Common genetic polymorphisms in Moyamoya and atherosclerotic disease in Europeans. Roder C, et al. Childs Nerv Syst, 2010 Aug 6. PMID 20694560.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study. Bressler J, et al. Am J Epidemiol, 2010 Jan 1. PMID 19955471.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.A common variant in MTHFD1L is associated with neural tube defects and mRNA splicing efficiency. Parle-McDermott A, et al. Hum Mutat, 2009 Dec. PMID 19777576.

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$ 315.00
Cat# AT2927a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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