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MVD Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant MVD.

  • WB - MVD Antibody (monoclonal) (M01) AT2940a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
  • WB - MVD Antibody (monoclonal) (M01) AT2940a
    MVD monoclonal antibody (M01), clone 2A7 Western Blot analysis of MVD expression in A-431 ( (Cat # AT2940a )
  • WB - MVD Antibody (monoclonal) (M01) AT2940a
    Western Blot analysis of MVD expression in transfected 293T cell line by MVD monoclonal antibody (M01), clone 2A7.

    Lane 1: MVD transfected lysate(43.4 KDa).
    Lane 2: Non-transfected lysate.
  • IF - MVD Antibody (monoclonal) (M01) AT2940a
    Immunofluorescence of monoclonal antibody to MVD on A-431 cell. [antibody concentration 10 ug/ml]
  • E - MVD Antibody (monoclonal) (M01) AT2940a
    Detection limit for recombinant GST tagged MVD is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P53602
Other Accession NM_002461
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2A7
Calculated MW 43405 Da
Additional Information
Gene ID 4597
Other Names Diphosphomevalonate decarboxylase, Mevalonate (diphospho)decarboxylase, MDDase, Mevalonate pyrophosphate decarboxylase, MVD, MPD
Target/Specificity MVD (NP_002452, 301 a.a. ~ 398 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMVD Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. Voynova NE, et al. Arch Biochem Biophys, 2008 Dec 1. PMID 18823933.Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. Lu Y, et al. J Lipid Res, 2008 Dec. PMID 18660489.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.

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$ 315.00
Cat# AT2940a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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