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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   NDN Antibody (monoclonal) (M07)   

NDN Antibody (monoclonal) (M07)

Mouse monoclonal antibody raised against a partial recombinant NDN.

  • WB - NDN Antibody (monoclonal) (M07) AT2989a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.11 KDa) .
  • WB - NDN Antibody (monoclonal) (M07) AT2989a
    NDN monoclonal antibody (M07), clone 2D11 Western Blot analysis of NDN expression in U-2 OS ( (Cat # AT2989a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99608
Other Accession NM_002487
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2D11
Calculated MW 36086 Da
Additional Information
Gene ID 4692
Other Names Necdin, NDN
Target/Specificity NDN (NP_002478, 222 a.a. ~ 321 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsNDN Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed exclusively from the paternal allele. Studies in mouse suggest that the protein encoded by this gene may suppress growth in postmitotic neurons.


Necdin: a multi functional protein with potential tumor suppressor role? Chapman EJ, et al. Mol Carcinog, 2009 Nov. PMID 19626646.[Regulation of neuronal development by the imprinted gene Necdin] Yoshikawa K. No To Hattatsu, 2009 May. PMID 19517793.Nogo-A inhibits necdin-accelerated neurite outgrowth by retaining necdin in the cytoplasm. Liu X, et al. Mol Cell Neurosci, 2009 May. PMID 19386232.A common variant in DRD3 receptor is associated with autism spectrum disorder. de Krom M, et al. Biol Psychiatry, 2009 Apr 1. PMID 19058789.Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. Lu Y, et al. J Lipid Res, 2008 Dec. PMID 18660489.

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$ 315.00
Cat# AT2989a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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