NEK2 Antibody (monoclonal) (M11)
Mouse monoclonal antibody raised against a partial recombinant NEK2.
|Application ||WB, IF|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||51763 Da|
|Other Names||Serine/threonine-protein kinase Nek2, HSPK 21, Never in mitosis A-related kinase 2, NimA-related protein kinase 2, NimA-like protein kinase 1, NEK2, NEK2A, NLK1|
|Target/Specificity||NEK2 (AAH43502, 331 a.a. ~ 445 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||NEK2 Antibody (monoclonal) (M11) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Involvement of a centrosomal protein kendrin in the maintenance of centrosome cohesion by modulating Nek2A kinase activity. Matsuo K, et al. Biochem Biophys Res Commun, 2010 Jul 23. PMID 20599736.The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2. Zeng X, et al. Oncogene, 2010 Sep 9. PMID 20581865.Centrosome-related genes, genetic variation, and risk of breast cancer. Olson JE, et al. Breast Cancer Res Treat, 2010 May 28. PMID 20508983.Three genetic developmental stages of papillary renal cell tumors: duplication of chromosome 1q marks fatal progression. Szponar A, et al. Int J Cancer, 2009 May 1. PMID 19123481.Nek2 as a novel molecular target for the treatment of breast carcinoma. Tsunoda N, et al. Cancer Sci, 2009 Jan. PMID 19038001.
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