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NEUROD1 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT3023a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
NEUROD1 Antibody (monoclonal) (M01) - Product info | |
| Application | IF, WB
|
| Primary Accession | Q13562 |
| Reactivity | Human |
| Concentration | 1 mg/ml |
| Isotype | IgG2a Kappa |
| Clone Names | 3H8 |
| Calculated MW | 39920 Da |
NEUROD1 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 4760 | |
| Other Names BETA2, BHF1, NEURODneurogenic differentiation 1 | |
| Target/Specificity NEUROD1 (AAH09046, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions NEUROD1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
NEUROD1 Antibody (monoclonal) (M01) - Related products
AP2021a: NeuroD1 Antibody (N-term)
AP2021b: NeuroD1 Antibody (C-term)
RI13562: NEUROD1 predesign siRNA
DC02567: Human NEUROD1 cDNA Clone
LY11789a: NEUROD1 Over-expression Lysate
BP2021a: NeuroD1 Antibody (N-term) Blocking Peptide
NEUROD1 Antibody (monoclonal) (M01) - Application data
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Immunofluorescence of monoclonal antibody to NEUROD1 (AT3023a) on HeLa cell . [antibody concentration 10 ug/ml]
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Western Blot analysis of NEUROD1 expression in transfected 293T cell line by NEUROD1 monoclonal antibody (M01), clone 3H8.
Lane 1: NEUROD1 transfected lysate(39.9 KDa).
Lane 2: Non-transfected lysate.
NEUROD1 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
REFERENCES
COMMON VARIANTS IN 40 GENES ASSESSED FOR DIABETES INCIDENCE AND RESPONSE TO METFORMIN AND LIFESTYLE INTERVENTIONS IN THE DIABETES PREVENTION PROGRAM. Jablonski KA, et al. Diabetes, 2010 Aug 3. PMID 20682687.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Homozygous mutations in NEUROD1 are responsible for a novel syndrome of permanent neonatal diabetes and neurological abnormalities. Rubio-Cabezas O, et al. Diabetes, 2010 Sep. PMID 20573748.Identification of type 2 diabetes-associated combination of SNPs using support vector machine. Ban HJ, et al. BMC Genet, 2010 Apr 23. PMID 20416077.Retinopathy and nephropathy in type 1 diabetic patients--association with polymorphysms of vitamin D-receptor, TNF, Neuro-D and IL-1 receptor 1 genes. Bu?an K, et al. Coll Antropol, 2009 Dec. PMID 20120526.
