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NGB Antibody (monoclonal) (M02)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT3045a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
NGB Antibody (monoclonal) (M02) - Product info | |
| Primary Accession | Q9NPG2 |
| Reactivity | Human |
| Isotype | IgG1 kappa |
| Clone Names | 1A11-A9 |
| Calculated MW | 16933 Da |
NGB Antibody (monoclonal) (M02) - Additional info | |
| Gene ID 58157 | |
| Other Names neuroglobin | |
| Target/Specificity NGB (AAH32509, 1 a.a. ~ 152 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions NGB Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. | |
NGB Antibody (monoclonal) (M02) - Related products
NGB Antibody (monoclonal) (M02) - Application data
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Detection limit for recombinant GST tagged NGB is approximately 0.1ng/ml as a capture antibody.
NGB Antibody (monoclonal) (M02) - Research Areas
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BACKGROUND
This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.
REFERENCES
Neuroglobin genetic polymorphisms and their relationship to functional outcomes after traumatic brain injury. Chuang PY, et al. J Neurotrauma, 2010 Jun. PMID 20345238.Spectroscopic study on acid-induced unfolding and refolding of apo-neuroglobin. Mu J, et al. Spectrochim Acta A Mol Biomol Spectrosc, 2010 May. PMID 20227336.Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death. Raychaudhuri S, et al. Apoptosis, 2010 Apr. PMID 20091232.Neuroglobin expression in ischemic stroke. Jin K, et al. Stroke, 2010 Mar. PMID 20075359.Unusual stability of human neuroglobin at low pH--molecular mechanisms and biological significance. Picotti P, et al. FEBS J, 2009 Dec. PMID 19860834.
