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NR1H2 Antibody (monoclonal) (M04)

Mouse monoclonal antibody raised against a full length recombinant NR1H2.

  • WB - NR1H2 Antibody (monoclonal) (M04) AT3097a
    NR1H2 monoclonal antibody (M04), clone 1E1. Western Blot analysis of NR1H2 expression in PC-12(Cat # L012V1 ).
  • WB - NR1H2 Antibody (monoclonal) (M04) AT3097a
    NR1H2 monoclonal antibody (M04), clone 1E1 Western Blot analysis of NR1H2 expression in IMR-32 ( (Cat # AT3097a )
  • IF - NR1H2 Antibody (monoclonal) (M04) AT3097a
    Immunofluorescence of monoclonal antibody to NR1H2 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - NR1H2 Antibody (monoclonal) (M04) AT3097a
    Detection limit for recombinant GST tagged NR1H2 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55055
Other Accession BC007790
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 10
Calculated MW 50974 Da
Additional Information
Gene ID 7376
Other Names Oxysterols receptor LXR-beta, Liver X receptor beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2, Ubiquitously-expressed nuclear receptor, NR1H2, LXRB, NER, UNR
Target/Specificity NR1H2 (AAH07790.1, 1 a.a. ~ 461 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsNR1H2 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.LXR activation inhibits chemokine-induced CD4-positive lymphocyte migration. Walcher D, et al. Basic Res Cardiol, 2010 Jul. PMID 20364260.Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway. Christoffolete MA, et al. J Endocrinol, 2010 May. PMID 20176747.GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response. Venteclef N, et al. Genes Dev, 2010 Feb 15. PMID 20159957.Integrative predictive model of coronary artery calcification in atherosclerosis. McGeachie M, et al. Circulation, 2009 Dec 15. PMID 19948975.

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$ 315.00
Cat# AT3097a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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