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NSDHL Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant NSDHL.

  • WB - NSDHL Antibody (monoclonal) (M01) AT3118a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - NSDHL Antibody (monoclonal) (M01) AT3118a
    NSDHL monoclonal antibody (M01), clone 6E3. Western Blot analysis of NSDHL expression in PC-12.
  • WB - NSDHL Antibody (monoclonal) (M01) AT3118a
    NSDHL monoclonal antibody (M01), clone 6E3. Western Blot analysis of NSDHL expression in Raw 264.7.
  • WB - NSDHL Antibody (monoclonal) (M01) AT3118a
    NSDHL monoclonal antibody (M01), clone 6E3. Western Blot analysis of NSDHL expression in A-431.
  • E - NSDHL Antibody (monoclonal) (M01) AT3118a
    Detection limit for recombinant GST tagged NSDHL is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15738
Other Accession NM_015922
Reactivity Human, Mouse, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 6E4
Calculated MW 41900 Da
Additional Information
Gene ID 50814
Other Names Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating, Protein H105e3, NSDHL, H105E3
Target/Specificity NSDHL (NP_057006, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsNSDHL Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.


Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. Lipkin SM, et al. Cancer Prev Res (Phila), 2010 May. PMID 20403997.Significant contributions of the extraembryonic membranes and maternal genotype to the placental pathology in heterozygous Nsdhl deficient female embryos. Cunningham D, et al. Hum Mol Genet, 2010 Jan 15. PMID 19880419.The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. Persson B, et al. Chem Biol Interact, 2009 Mar 16. PMID 19027726.Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. Lu Y, et al. J Lipid Res, 2008 Dec. PMID 18660489.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.

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$ 315.00
Cat# AT3118a
(40 western blots)
Availability: 7-10 days
Bulk Size
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