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OTX1 Antibody (monoclonal) (M07)

Mouse monoclonal antibody raised against a partial recombinant OTX1.

     
  • IF - OTX1 Antibody (monoclonal) (M07) AT3160a
    Immunofluorescence of monoclonal antibody to OTX1 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • WB - OTX1 Antibody (monoclonal) (M07) AT3160a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.51 KDa) .
    detail
  • E - OTX1 Antibody (monoclonal) (M07) AT3160a
    Detection limit for recombinant GST tagged OTX1 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession P32242
Other Accession NM_014562
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3A5
Calculated MW 37327 Da
Additional Information
Gene ID 5013
Other Names Homeobox protein OTX1, Orthodenticle homolog 1, OTX1
Target/Specificity OTX1 (NP_055377, 10 a.a. ~ 116 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsOTX1 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.

References

Expression of the homeobox genes OTX2 and OTX1 in the early developing human brain. Larsen KB, et al. J Histochem Cytochem, 2010 Jul. PMID 20354145.Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma. Omodei D, et al. Am J Pathol, 2009 Dec. PMID 19893048.Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Eeles RA, et al. Nat Genet, 2009 Oct. PMID 19767753.Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967.Expression of the homeobox genes PAX6, OTX2, and OTX1 in the early human fetal retina. Larsen KB, et al. Int J Dev Neurosci, 2009 Aug. PMID 19414065.

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$ 350.00
Cat# AT3160a
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Availability: 7-10 days
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