OTX1 Antibody (monoclonal) (M07)
Mouse monoclonal antibody raised against a partial recombinant OTX1.
|Application ||WB, IF, E|
|Calculated MW||37327 Da|
|Other Names||Homeobox protein OTX1, Orthodenticle homolog 1, OTX1|
|Target/Specificity||OTX1 (NP_055377, 10 a.a. ~ 116 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||OTX1 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.
Expression of the homeobox genes OTX2 and OTX1 in the early developing human brain. Larsen KB, et al. J Histochem Cytochem, 2010 Jul. PMID 20354145.Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma. Omodei D, et al. Am J Pathol, 2009 Dec. PMID 19893048.Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Eeles RA, et al. Nat Genet, 2009 Oct. PMID 19767753.Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967.Expression of the homeobox genes PAX6, OTX2, and OTX1 in the early human fetal retina. Larsen KB, et al. Int J Dev Neurosci, 2009 Aug. PMID 19414065.
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