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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PAK3 Antibody (monoclonal) (M07)   

PAK3 Antibody (monoclonal) (M07)

Mouse monoclonal antibody raised against a partial recombinant PAK3.

  • WB - PAK3 Antibody (monoclonal) (M07) AT3174a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.53 KDa) .
  • WB - PAK3 Antibody (monoclonal) (M07) AT3174a
    PAK3 monoclonal antibody (M07), clone 1H7 Western Blot analysis of PAK3 expression in NIH/3T3 ( (Cat # AT3174a )
  • IF - PAK3 Antibody (monoclonal) (M07) AT3174a
    Immunofluorescence of monoclonal antibody to PAK3 on NIH/3T3 cell. [antibody concentration 10 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75914
Other Accession NM_002578
Reactivity Human, Mouse
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1H7
Calculated MW 62310 Da
Additional Information
Gene ID 5063
Other Names Serine/threonine-protein kinase PAK 3, Beta-PAK, Oligophrenin-3, p21-activated kinase 3, PAK-3, PAK3, OPHN3
Target/Specificity PAK3 (NP_002569, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPAK3 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.


1.A 14-3-3?^ dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIII?] to regulate post-Golgi carrier formation.Valente C, Turacchio G, Mariggio S, Pagliuso A, Gaibisso R, Di Tullio G, Santoro M, Formiggini F, Spano S, Piccini D, Polishchuk RS, Colanzi A, Luini A, Corda D.Nat Cell Biol. 2012 Feb 26. doi: 10.1038/ncb2445. [Epub ahead of print]

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$ 315.00
Cat# AT3174a
(40 western blots)
Availability: 7-10 days
Bulk Size
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