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PAX2 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant PAX2.

     
  • WB - PAX2 Antibody (monoclonal) (M02) AT3189a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
    detail
  • WB - PAX2 Antibody (monoclonal) (M02) AT3189a
    PAX2 monoclonal antibody (M02), clone 2E4 Western Blot analysis of PAX2 expression in PC-12 ( (Cat # AT3189a )
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q02962
Other Accession NM_000278
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2E5
Calculated MW 44706 Da
Additional Information
Gene ID 5076
Other Names Paired box protein Pax-2, PAX2
Target/Specificity PAX2 (NP_000269, 194 a.a. ~ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPAX2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

References

1.c-Jun is essential for the induction of Il-1?] gene expression in in vitro activated Bergmann glial cells.Albanito L, Reddy CE, Musti AM.Glia. 2011 Sep 21. doi: 10.1002/glia.21244.2.The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma.Doberstein K, Pfeilschifter J, Gutwein P.Carcinogenesis. 2011 Sep 16.

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$ 350.00
Cat# AT3189a
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Availability: 7-10 days
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