PAX9 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full-length recombinant PAX9.
|Calculated MW||36310 Da|
|Other Names||Paired box protein Pax-9, PAX9|
|Target/Specificity||PAX9 (NP_006185, 205 a.a. ~ 300 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||PAX9 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 9 gene is unknown but it may involve development of stratified squamous epithelia as well as various organs and skeletal elements.
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.Mutations in the PAX9 gene in sporadic oligodontia. Pawlowska E, et al. Orthod Craniofac Res, 2010 Aug. PMID 20618716.Association between genetic variants of reported candidate genes or regions and risk of cleft lip with or without cleft palate in the polish population. Mostowska A, et al. Birth Defects Res A Clin Mol Teratol, 2010 Jul. PMID 20544801.A 223-kb de novo deletion of PAX9 in a patient with oligodontia. Haldeman-Englert CR, et al. J Craniofac Surg, 2010 May. PMID 20485064.Genetics and human malformations. Mues G, et al. J Craniofac Surg, 2009 Sep. PMID 19816326.
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