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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   PCMT1 Antibody (monoclonal) (M02)   

PCMT1 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant PCMT1.

  • WB - PCMT1 Antibody (monoclonal) (M02) AT3235a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) .
  • WB - PCMT1 Antibody (monoclonal) (M02) AT3235a
    PCMT1 monoclonal antibody (M02), clone 1D6 Western Blot analysis of PCMT1 expression in HeLa ( (Cat # AT3235a )
  • WB - PCMT1 Antibody (monoclonal) (M02) AT3235a
    PCMT1 monoclonal antibody (M02), clone 1D6. Western Blot analysis of PCMT1 expression in PC-12 ( (Cat # AT3235a )
  • WB - PCMT1 Antibody (monoclonal) (M02) AT3235a
    PCMT1 monoclonal antibody (M02), clone 1D6. Western Blot analysis of PCMT1 expression in Raw 264.7 ( (Cat # AT3235a )
  • WB - PCMT1 Antibody (monoclonal) (M02) AT3235a
    PCMT1 monoclonal antibody (M02), clone 1D6. Western Blot analysis of PCMT1 expression in NIH/3T3 ( (Cat # AT3235a )
  • E - PCMT1 Antibody (monoclonal) (M02) AT3235a
    Detection limit for recombinant GST tagged PCMT1 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22061
Other Accession NM_005389
Reactivity Human, Mouse, Rat
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1D6
Calculated MW 24636 Da
Additional Information
Gene ID 5110
Other Names Protein-L-isoaspartate(D-aspartate) O-methyltransferase, PIMT, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PCMT1
Target/Specificity PCMT1 (NP_005380, 117 a.a. ~ 225 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPCMT1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 May 14. PMID 20471030.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1). Franke B, et al. Birth Defects Res A Clin Mol Teratol, 2009 Mar. PMID 19161160.Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2009 Jul. PMID 19110265.

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$ 315.00
Cat# AT3235a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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