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PDCD6 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant PDCD6.

  • WB - PDCD6 Antibody (monoclonal) (M01) AT3246a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - PDCD6 Antibody (monoclonal) (M01) AT3246a
    PDCD6 monoclonal antibody (M01), clone 2B4 Western Blot analysis of PDCD6 expression in HeLa ( (Cat # AT3246a )
  • IF - PDCD6 Antibody (monoclonal) (M01) AT3246a
    Immunofluorescence of monoclonal antibody to PDCD6 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - PDCD6 Antibody (monoclonal) (M01) AT3246a
    Detection limit for recombinant GST tagged PDCD6 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75340
Other Accession BC012384
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2B4
Calculated MW 21868 Da
Additional Information
Gene ID 10016
Other Names Programmed cell death protein 6, Apoptosis-linked gene 2 protein, Probable calcium-binding protein ALG-2, PDCD6, ALG2
Target/Specificity PDCD6 (AAH12384, 92 a.a. ~ 191 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPDCD6 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.


Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1. Vergarajauregui S, et al. J Biol Chem, 2009 Dec 25. PMID 19864416.Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101. Okumura M, et al. Biochem Biophys Res Commun, 2009 Aug 14. PMID 19520058.Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2. Suzuki H, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008 Nov 1. PMID 18997320.Identification of prognostic biomarkers in gastric cancer using endoscopic biopsy samples. Yamada Y, et al. Cancer Sci, 2008 Nov. PMID 18957060.Structural basis for Ca2+ -dependent formation of ALG-2/Alix peptide complex: Ca2+/EF3-driven arginine switch mechanism. Suzuki H, et al. Structure, 2008 Oct 8. PMID 18940611.

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$ 315.00
Cat# AT3246a
(40 western blots)
Availability: 7-10 days
Bulk Size
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