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PDCD6IP Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant PDCD6IP.

  • WB - PDCD6IP Antibody (monoclonal) (M01) AT3247a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) .
  • IF - PDCD6IP Antibody (monoclonal) (M01) AT3247a
    Immunofluorescence of monoclonal antibody to PDCD6IP on HeLa cell. [antibody concentration 10 ug/ml]
  • E - PDCD6IP Antibody (monoclonal) (M01) AT3247a
    Detection limit for recombinant GST tagged PDCD6IP is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WUM4
Other Accession BC020066
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a kappa
Clone Names 3C4
Calculated MW 96023 Da
Additional Information
Gene ID 10015
Other Names Programmed cell death 6-interacting protein, PDCD6-interacting protein, ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, PDCD6IP, AIP1, ALIX, KIAA1375
Target/Specificity PDCD6IP (AAH20066, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPDCD6IP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.


Significance of the YLDL motif in the M protein and Alix/AIP1 for Sendai virus budding in the context of virus infection. Irie T, et al. Virology, 2010 Sep 30. PMID 20605035.The ESCRT-associated protein Alix recruits the ubiquitin ligase Nedd4-1 to facilitate HIV-1 release through the LYPXnL L domain motif. Sette P, et al. J Virol, 2010 Aug. PMID 20519395.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Discovery of novel human transcript variants by analysis of intronic single-block EST with polyadenylation site. Wang P, et al. BMC Genomics, 2009 Nov 12. PMID 19906316.Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Chen HY, et al. Proc Natl Acad Sci U S A, 2009 Aug 25. PMID 19706535.

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$ 315.00
Cat# AT3247a
(40 western blots)
Availability: 7-10 days
Bulk Size
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