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PFN2 Antibody (monoclonal) (M05)

Mouse monoclonal antibody raised against a partial recombinant PFN2.

  • WB - PFN2 Antibody (monoclonal) (M05) AT3275a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - PFN2 Antibody (monoclonal) (M05) AT3275a
    PFN2 monoclonal antibody (M05), clone 6G3. Western Blot analysis of PFN2 expression in HeLa ( (Cat # AT3275a )
  • E - PFN2 Antibody (monoclonal) (M05) AT3275a
    Detection limit for recombinant GST tagged PFN2 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35080
Other Accession NM_002628
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 6G3
Calculated MW 15046 Da
Additional Information
Gene ID 5217
Other Names Profilin-2, Profilin II, PFN2
Target/Specificity PFN2 (NP_002619, 41 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPFN2 Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.


Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation. Shao J, et al. Mol Cell Biol, 2008 Sep. PMID 18573880.Identification of Rgl3 as a potential binding partner for Rap-family small G-proteins and profilin II. Xu J, et al. Cell Signal, 2007 Jul. PMID 17382517.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.Profilin regulates the activity of p42POP, a novel Myb-related transcription factor. Lederer M, et al. J Cell Sci, 2005 Jan 15. PMID 15615774.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

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$ 315.00
Cat# AT3275a
(40 western blots)
Availability: 7-10 days
Bulk Size
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