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PIK3C2B Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant PIK3C2B.

  • WB - PIK3C2B Antibody (monoclonal) (M02) AT3309a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - PIK3C2B Antibody (monoclonal) (M02) AT3309a
    PIK3C2B monoclonal antibody (M02), clone 3E5 Western Blot analysis of PIK3C2B expression in A-431 ( (Cat # AT3309a )
  • IF - PIK3C2B Antibody (monoclonal) (M02) AT3309a
    Immunofluorescence of monoclonal antibody to PIK3C2B on A-431 cell. [antibody concentration 10 ug/ml]
  • E - PIK3C2B Antibody (monoclonal) (M02) AT3309a
    Detection limit for recombinant GST tagged PIK3C2B is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00750
Other Accession NM_002646
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3E6
Calculated MW 184768 Da
Additional Information
Gene ID 5287
Other Names Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, PI3K-C2-beta, PtdIns-3-kinase C2 subunit beta, C2-PI3K, Phosphoinositide 3-kinase-C2-beta, PIK3C2B
Target/Specificity PIK3C2B (NP_002637, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPIK3C2B Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations ( 0 )


The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Rua?o G, et al. Pharmacogenomics, 2010 Jul. PMID 20602615.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer. Koutros S, et al. Cancer Res, 2010 Mar 15. PMID 20197460.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.

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$ 315.00
Cat# AT3309a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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