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>   home   >   Products   >   Primary Antibodies   >   PILRA Antibody (monoclonal) (M01)   

PILRA Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant PILRA.

  • WB - PILRA Antibody (monoclonal) (M01) AT3311a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (50.6 KDa) .
  • WB - PILRA Antibody (monoclonal) (M01) AT3311a
    PILRA monoclonal antibody (M01), clone 3C2 Western Blot analysis of PILRA expression in Hela S3 NE ( (Cat # AT3311a )
  • E - PILRA Antibody (monoclonal) (M01) AT3311a
    Detection limit for recombinant GST tagged PILRA is approximately 3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UKJ1
Other Accession BC017812
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 3C2
Calculated MW 34005 Da
Additional Information
Gene ID 29992
Other Names Paired immunoglobulin-like type 2 receptor alpha, Cell surface receptor FDF03, Inhibitory receptor PILR-alpha, PILRA
Target/Specificity PILRA (AAH17812, 1 a.a. ~ 226 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPILRA Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.


Differential effects on cell fusion activity of mutations in herpes simplex virus 1 glycoprotein B (gB) dependent on whether a gD receptor or a gB receptor is overexpressed. Fan Q, et al. J Virol, 2009 Aug. PMID 19457990.Entry of herpes simplex virus 1 and other alphaherpesviruses via the paired immunoglobulin-like type 2 receptor alpha. Arii J, et al. J Virol, 2009 May. PMID 19244335.PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B. Satoh T, et al. Cell, 2008 Mar 21. PMID 18358807.Expression, crystallization and preliminary X-ray diffraction analysis of human paired Ig-like type 2 receptor alpha (PILRalpha). Tabata S, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008 Jan 1. PMID 18097101.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

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$ 315.00
Cat# AT3311a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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