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PITX1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant PITX1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP, E |
|---|---|
| Primary Accession | P78337 |
| Other Accession | NM_002653 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 5G4 |
| Calculated MW | 34128 Da |
| Gene ID | 5307 |
|---|---|
| Other Names | Pituitary homeobox 1, Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1, PITX1, BFT, PTX1 |
| Target/Specificity | PITX1 (NP_002644, 225 a.a. ~ 313 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | PITX1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
References
1.The c-Abl tyrosine kinase stabilizes Pitx1 in the apoptotic response to DNA damage.Yamaguchi T, Miki Y, Yoshida K.Apoptosis. 2010 Aug;15(8):927-35.2.Transcriptional activation of p53 by Pitx1.Liu DX, Lobie PE.Cell Death Differ. 2007 Nov;14(11):1893-907. Epub 2007 Aug 31.
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