POLE2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant POLE2.
|Reactivity||Human, Mouse, Rat|
|Calculated MW||59537 Da|
|Other Names||DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B, POLE2, DPE2|
|Target/Specificity||POLE2 (NP_002683, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||POLE2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Mutations/polymorphisms in the 55 kDa subunit of DNA polymerase epsilon in human colorectal cancer. Zhou Q, et al. Cancer Genomics Proteomics, 2009 Nov-Dec. PMID 20065316.Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. Michiels S, et al. Carcinogenesis, 2009 May. PMID 19237606.The solution structure of the amino-terminal domain of human DNA polymerase epsilon subunit B is homologous to C-domains of AAA+ proteins. Nuutinen T, et al. Nucleic Acids Res, 2008 Sep. PMID 18676977.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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