POLR2I Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant POLR2I.
|Application ||WB, E|
|Calculated MW||14523 Da|
|Other Names||DNA-directed RNA polymerase II subunit RPB9, RNA polymerase II subunit B9, DNA-directed RNA polymerase II subunit I, RNA polymerase II 145 kDa subunit, RPB145, POLR2I|
|Target/Specificity||POLR2I (AAH17112, 26 a.a. ~ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||POLR2I Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity.
Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Will diverse Tat interactions lead to novel antiretroviral drug targets? Harrich D, et al. Curr Drug Targets, 2006 Dec. PMID 17168834.The regulation of HIV-1 transcription: molecular targets for chemotherapeutic intervention. Stevens M, et al. Med Res Rev, 2006 Sep. PMID 16838299.Inhibition of HIV-1 virus replication using small soluble Tat peptides. Agbottah E, et al. Virology, 2006 Feb 20. PMID 16289656.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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