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PPP1R14A Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant PPP1R14A.

  • WB - PPP1R14A Antibody (monoclonal) (M01) AT3408a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (41.91 KDa) .
  • WB - PPP1R14A Antibody (monoclonal) (M01) AT3408a
    Western Blot analysis of PPP1R14A expression in transfected 293T cell line by PPP1R14A monoclonal antibody (M01), clone 3A7.

    Lane 1: PPP1R14A transfected lysate(16.7 KDa).
    Lane 2: Non-transfected lysate.
  • E - PPP1R14A Antibody (monoclonal) (M01) AT3408a
    Detection limit for recombinant GST tagged PPP1R14A is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96A00
Other Accession BC021089
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 3A7
Calculated MW 16693 Da
Additional Information
Gene ID 94274
Other Names Protein phosphatase 1 regulatory subunit 14A, 17 kDa PKC-potentiated inhibitory protein of PP1, Protein kinase C-potentiated inhibitor protein of 17 kDa, CPI-17, PPP1R14A, CPI17, PPP1INL
Target/Specificity PPP1R14A (AAH21089, 1 a.a. ~ 147 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPPP1R14A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase (see MIM 603768). Inhibition leads to increased myosin phosphorylation and enhances smooth muscle contraction in the absence of increased intracellular Ca(2+) concentration.


Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Gudmundsson J, et al. Nat Genet, 2009 Oct. PMID 19767754.Functional inactivation of NF2/merlin in human mesothelioma. Thurneysen C, et al. Lung Cancer, 2009 May. PMID 18835652.CPI-17 silencing-reduced responsiveness in control and TNF-alpha-treated human bronchi. Morin C, et al. Am J Respir Cell Mol Biol, 2008 Dec. PMID 18757304.Protein microarray analysis identifies human cellular prion protein interactors. Satoh J, et al. Neuropathol Appl Neurobiol, 2009 Feb. PMID 18482256.Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor. Lartey J, et al. Biol Reprod, 2007 Jun. PMID 17301291.

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$ 315.00
Cat# AT3408a
(40 western blots)
Availability: 7-10 days
Bulk Size
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