PPP1R14A Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant PPP1R14A.
|Application ||WB, E|
|Calculated MW||16693 Da|
|Other Names||Protein phosphatase 1 regulatory subunit 14A, 17 kDa PKC-potentiated inhibitory protein of PP1, Protein kinase C-potentiated inhibitor protein of 17 kDa, CPI-17, PPP1R14A, CPI17, PPP1INL|
|Target/Specificity||PPP1R14A (AAH21089, 1 a.a. ~ 147 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||PPP1R14A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase (see MIM 603768). Inhibition leads to increased myosin phosphorylation and enhances smooth muscle contraction in the absence of increased intracellular Ca(2+) concentration.
Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Gudmundsson J, et al. Nat Genet, 2009 Oct. PMID 19767754.Functional inactivation of NF2/merlin in human mesothelioma. Thurneysen C, et al. Lung Cancer, 2009 May. PMID 18835652.CPI-17 silencing-reduced responsiveness in control and TNF-alpha-treated human bronchi. Morin C, et al. Am J Respir Cell Mol Biol, 2008 Dec. PMID 18757304.Protein microarray analysis identifies human cellular prion protein interactors. Satoh J, et al. Neuropathol Appl Neurobiol, 2009 Feb. PMID 18482256.Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor. Lartey J, et al. Biol Reprod, 2007 Jun. PMID 17301291.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.