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PRDX3 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant PRDX3.

  • WB - PRDX3 Antibody (monoclonal) (M01) AT3422a
    Western Blot analysis of PRDX3 expression in transfected 293T cell line by PRDX3 monoclonal antibody (M01), clone 1E3-B2.

    Lane 1: PRDX3 transfected lysate (Predicted MW: 27.7 KDa).
    Lane 2: Non-transfected lysate.
  • IF - PRDX3 Antibody (monoclonal) (M01) AT3422a
    Immunofluorescence of monoclonal antibody to PRDX3 on HeLa cell . [antibody concentration 10 ug/ml]
  • IP - PRDX3 Antibody (monoclonal) (M01) AT3422a
    Immunoprecipitation of PRDX3 transfected lysate using anti-PRDX3 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PRDX3 MaxPab rabbit polyclonal antibody.
  • E - PRDX3 Antibody (monoclonal) (M01) AT3422a
    Detection limit for recombinant GST tagged PRDX3 is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30048
Other Accession BC002685
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1E3-B2
Calculated MW 27693 Da
Additional Information
Gene ID 10935
Other Names Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1
Target/Specificity PRDX3 (AAH02685, 1 a.a. ~ 256 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPRDX3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.


[Expression of peroxiredoxin III cervical lesions] Li LQ, et al. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi, 2009 Dec. PMID 20718351.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Silencing the Peroxiredoxin III gene inhibits cell proliferation in breast cancer. Chua PJ, et al. Int J Oncol, 2010 Feb. PMID 20043069.Knockdown of the type 3 iodothyronine deiodinase (D3) interacting protein peroxiredoxin 3 decreases D3-mediated deiodination in intact cells. Aerts G, et al. Endocrinology, 2009 Nov. PMID 19819956.Redox potential and peroxide reactivity of human peroxiredoxin 3. Cox AG, et al. Biochemistry, 2009 Jul 14. PMID 19462976.

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$ 315.00
Cat# AT3422a
(40 western blots)
Availability: 7-10 days
Bulk Size
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