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PSAP Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant PSAP.

  • WB - PSAP Antibody (monoclonal) (M01) AT3448a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (81.29 KDa) .
  • WB - PSAP Antibody (monoclonal) (M01) AT3448a
    Western Blot analysis of PSAP expression in transfected 293T cell line by PSAP monoclonal antibody (M01), clone 1D1-C12.

    Lane 1: PSAP transfected lysate(58.1 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - PSAP Antibody (monoclonal) (M01) AT3448a
    Immunoperoxidase of monoclonal antibody to PSAP on formalin-fixed paraffin-embedded human spleen tissue. [antibody concentration 5 ug/ml]
  • IP - PSAP Antibody (monoclonal) (M01) AT3448a
    Immunoprecipitation of PSAP transfected lysate using anti-PSAP monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PSAP MaxPab rabbit polyclonal antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07602
Other Accession BC001503
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a kappa
Clone Names 1D1-C12
Calculated MW 58113 Da
Additional Information
Gene ID 5660
Other Names Prosaposin, Proactivator polypeptide, Saposin-A, Protein A, Saposin-B-Val, Saposin-B, Cerebroside sulfate activator, CSAct, Dispersin, Sphingolipid activator protein 1, SAP-1, Sulfatide/GM1 activator, Saposin-C, A1 activator, Co-beta-glucosidase, Glucosylceramidase activator, Sphingolipid activator protein 2, SAP-2, Saposin-D, Component C, Protein C, PSAP, GLBA, SAP1
Target/Specificity PSAP (AAH01503, 18 a.a. ~ 524 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPSAP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.


1.Serum prosaposin levels are increased in patients with advanced prostate cancer.Koochekpour S, Hu S, Vellasco-Gonzalez C, Bernardo R, Azabdaftari G, Zhu G, Zhau HE, Chung LW, Vessella RL.Prostate. 2011 May 31. doi: 10.1002/pros.21427. [Epub ahead of print]

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$ 315.00
Cat# AT3448a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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