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PSCD2 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant CYTH2.

  • WB - PSCD2 Antibody (monoclonal) (M02) AT3450a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.09 KDa) .
  • WB - PSCD2 Antibody (monoclonal) (M02) AT3450a
    CYTH2 monoclonal antibody (M02), clone 6H5 Western Blot analysis of CYTH2 expression in PC-12 ( (Cat # AT3450a )
  • WB - PSCD2 Antibody (monoclonal) (M02) AT3450a
    Western Blot analysis of CYTH2 expression in transfected 293T cell line by CYTH2 monoclonal antibody (M02), clone 6H5.

    Lane 1: CYTH2 transfected lysate(46.5 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - PSCD2 Antibody (monoclonal) (M02) AT3450a
    Immunoperoxidase of monoclonal antibody to CYTH2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]
  • IF - PSCD2 Antibody (monoclonal) (M02) AT3450a
    Immunofluorescence of monoclonal antibody to CYTH2 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - PSCD2 Antibody (monoclonal) (M02) AT3450a
    Detection limit for recombinant GST tagged CYTH2 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99418
Other Accession NM_017457
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 6H5
Calculated MW 46546 Da
Additional Information
Gene ID 9266
Other Names Cytohesin-2, ARF exchange factor, ARF nucleotide-binding site opener, Protein ARNO, PH, SEC7 and coiled-coil domain-containing protein 2, CYTH2, ARNO, PSCD2, PSCD2L
Target/Specificity CYTH2 (NP_059431, 314 a.a. ~ 398 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPSCD2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.


1.ARNO regulates VEGF-dependent tissue responses by stabilizing endothelial VEGFR-2 surface expression.Mannell HK, Pircher J, Chaudhry DI, Alig SK, Koch EG, Mettler R, Pohl U, Krotz F.Cardiovasc Res. 2011 Nov 7.

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$ 315.00
Cat# AT3450a
(40 western blots)
Availability: 7-10 days
Bulk Size
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