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PSPH Antibody (monoclonal) (M06)

Mouse monoclonal antibody raised against a partial recombinant PSPH.

     
  • WB - PSPH Antibody (monoclonal) (M06) AT3477a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
    detail
  • WB - PSPH Antibody (monoclonal) (M06) AT3477a
    PSPH monoclonal antibody (M06), clone 3C1 Western Blot analysis of PSPH expression in Hela S3 NE ( (Cat # AT3477a )
    detail
  • E - PSPH Antibody (monoclonal) (M06) AT3477a
    Detection limit for recombinant GST tagged PSPH is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P78330
Other Accession NM_004577
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3C1
Calculated MW 25008 Da
Additional Information
Gene ID 5723
Other Names Phosphoserine phosphatase, PSP, PSPase, L-3-phosphoserine phosphatase, O-phosphoserine phosphohydrolase, PSPH
Target/Specificity PSPH (NP_004568, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPSPH Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome.

References

Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.How calcium inhibits the magnesium-dependent enzyme human phosphoserine phosphatase. Peeraer Y, et al. Eur J Biochem, 2004 Aug. PMID 15291819.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.Mutations responsible for 3-phosphoserine phosphatase deficiency. Veiga-da-Cunha M, et al. Eur J Hum Genet, 2004 Feb. PMID 14673469.

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$ 350.00
Cat# AT3477a
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