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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PTK7 Antibody (monoclonal) (M02)   

PTK7 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant PTK7.

  • WB - PTK7 Antibody (monoclonal) (M02) AT3488a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - PTK7 Antibody (monoclonal) (M02) AT3488a
    PTK7 monoclonal antibody (M02), clone 4C6 Western Blot analysis of PTK7 expression in A-431 ( (Cat # AT3488a )
  • IF - PTK7 Antibody (monoclonal) (M02) AT3488a
    Immunofluorescence of monoclonal antibody to PTK7 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - PTK7 Antibody (monoclonal) (M02) AT3488a
    Detection limit for recombinant GST tagged PTK7 is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13308
Other Accession NM_002821
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 4C6
Calculated MW 118392 Da
Additional Information
Gene ID 5754
Other Names Inactive tyrosine-protein kinase 7, Colon carcinoma kinase 4, CCK-4, Protein-tyrosine kinase 7, Pseudo tyrosine kinase receptor 7, Tyrosine-protein kinase-like 7, PTK7, CCK4
Target/Specificity PTK7 (NP_002812, 36 a.a. ~ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPTK7 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.


Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis. Shin WS, et al. Biochem Biophys Res Commun, 2008 Jul 11. PMID 18471990.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells. Katoh M, et al. Int J Mol Med, 2007 Sep. PMID 17671748.The GxxxG-containing transmembrane domain of the CCK4 oncogene does not encode preferential self-interactions. Kobus FJ, et al. Biochemistry, 2005 Feb 8. PMID 15683231.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.

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$ 315.00
Cat# AT3488a
(40 western blots)
Availability: 7-10 days
Bulk Size
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