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>   home   >   Products   >   Primary Antibodies   >   PURA Antibody (monoclonal) (M05)   

PURA Antibody (monoclonal) (M05)

Mouse monoclonal antibody raised against a partial recombinant PURA.

  • WB - PURA Antibody (monoclonal) (M05) AT3502a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - PURA Antibody (monoclonal) (M05) AT3502a
    PURA monoclonal antibody (M05), clone 3A9. Western Blot analysis of PURA expression in PC-12 ( (Cat # AT3502a )
  • E - PURA Antibody (monoclonal) (M05) AT3502a
    Detection limit for recombinant GST tagged PURA is approximately 10ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q00577
Other Accession NM_005859
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3A9
Calculated MW 34911 Da
Additional Information
Gene ID 5813
Other Names Transcriptional activator protein Pur-alpha, Purine-rich single-stranded DNA-binding protein alpha, PURA, PUR1
Target/Specificity PURA (NP_005850, 183 a.a. ~ 292 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPURA Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.


Purine-rich element binding protein (PUR) alpha induces endoplasmic reticulum stress response, and cell differentiation pathways in prostate cancer cells. Inoue T, et al. Prostate, 2009 Jun 1. PMID 19267365.Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. Martins-de-Souza D, et al. Eur Arch Psychiatry Clin Neurosci, 2009 Apr. PMID 19165527.Protective role of Puralpha to cisplatin. Kaminski R, et al. Cancer Biol Ther, 2008 Dec. PMID 18927497.Negative regulation of AbetaPP gene expression by pur-alpha. Darbinian N, et al. J Alzheimers Dis, 2008 Sep. PMID 18780968.Androgen receptor overexpression in prostate cancer linked to Pur alpha loss from a novel repressor complex. Wang LG, et al. Cancer Res, 2008 Apr 15. PMID 18413735.

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$ 315.00
Cat# AT3502a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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