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QPCT Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant QPCT.

  • WB - QPCT Antibody (monoclonal) (M01) AT3508a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
  • E - QPCT Antibody (monoclonal) (M01) AT3508a
    Detection limit for recombinant GST tagged QPCT is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16769
Other Accession NM_012413
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4E12
Calculated MW 40877 Da
Additional Information
Gene ID 25797
Other Names Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase, QC, sQC, Glutaminyl-tRNA cyclotransferase, Glutamyl cyclase, EC, QPCT
Target/Specificity QPCT (NP_036545, 262 a.a. ~ 359 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsQPCT Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.


A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project. Marroni F, et al. Circ Cardiovasc Genet, 2009 Aug. PMID 20031603.Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics. Stephan A, et al. FEBS J, 2009 Nov. PMID 19804409.Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery. Cynis H, et al. J Mol Biol, 2008 Jun 20. PMID 18486145.Computational evidence for the catalytic mechanism of glutaminyl cyclase. A DFT investigation. Calvaresi M, et al. Proteins, 2008 Nov 15. PMID 18470930.A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Huang KF, et al. Biochem J, 2008 Apr 1. PMID 18072935.

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$ 315.00
Cat# AT3508a
(40 western blots)
Availability: 7-10 days
Bulk Size
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