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RAB27A Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant RAB27A.

  • WB - RAB27A Antibody (monoclonal) (M01) AT3517a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - RAB27A Antibody (monoclonal) (M01) AT3517a
    RAB27A monoclonal antibody (M01), clone 4C1. Western Blot analysis of RAB27A expression in HL-60 ( (Cat # AT3517a )
  • E - RAB27A Antibody (monoclonal) (M01) AT3517a
    Detection limit for recombinant GST tagged RAB27A is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51159
Other Accession NM_004580
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4C1
Calculated MW 24868 Da
Additional Information
Gene ID 5873
Other Names Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27
Target/Specificity RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsRAB27A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.


Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2. Ohbayashi N, et al. Pigment Cell Melanoma Res, 2010 Jun. PMID 20370853.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India. Chattopadhyay I, et al. Mutat Res, 2010 Feb 2. PMID 20083228.Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations. Meeths M, et al. Pediatr Blood Cancer, 2010 Apr. PMID 19953648.Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Wood SM, et al. Blood, 2009 Nov 5. PMID 19704116.

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$ 315.00
Cat# AT3517a
(40 western blots)
Availability: 7-10 days
Bulk Size
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