RAD23A Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RAD23A.
|Application ||WB, E|
|Calculated MW||39609 Da|
|Other Names||UV excision repair protein RAD23 homolog A, HR23A, hHR23A, RAD23A|
|Target/Specificity||RAD23A (AAH14026, 151 a.a. ~ 250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RAD23A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
1.Cisplatin transiently up-regulates hHR23 expression through enhanced translational efficiency in A549 adenocarcinoma cells.Shen YH, Chen BR, Cherng SH, Chueh PJ, Tan X, Lin YW, Lin JC, Chuang SM.Toxicol Lett. 2011 Jul 2. [Epub ahead of print]
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