RAPGEF4 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RAPGEF4.
|Application ||WB, E|
|Calculated MW||115522 Da|
|Other Names||Rap guanine nucleotide exchange factor 4, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFII, RAPGEF4, CGEF2, EPAC2|
|Target/Specificity||RAPGEF4 (AAH24004, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RAPGEF4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells. Aumo L, et al. Endocrinology, 2010 May. PMID 20233795.Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. Karasik D, et al. J Bone Miner Res, 2010 Jul. PMID 20200953.Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome. Chakrabarti B, et al. Autism Res, 2009 Jun. PMID 19598235.Mechanism of Epac activation: structural and functional analyses of Epac2 hinge mutants with constitutive and reduced activities. Tsalkova T, et al. J Biol Chem, 2009 Aug 28. PMID 19553663.
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