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RDHE2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant RDHE2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8N3Y7 |
| Other Accession | BC037219 |
| Reactivity | Human, Mouse, Rat |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 3G8 |
| Calculated MW | 34095 Da |
| Gene ID | 195814 |
|---|---|
| Other Names | Epidermal retinol dehydrogenase 2, EPHD-2, RDH-E2, Retinal short-chain dehydrogenase reductase 2, retSDR2, Short-chain dehydrogenase/reductase family 16C member 5, SDR16C5, RDHE2 |
| Target/Specificity | RDHE2 (AAH37219, 26 a.a. ~ 309 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RDHE2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).
References
The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. Zhao J, et al. BMC Med Genet, 2010 Jun 14. PMID 20546612.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. Soranzo N, et al. PLoS Genet, 2009 Apr. PMID 19343178.Characterization of key residues and membrane association domains in retinol dehydrogenase 10. Takahashi Y, et al. Biochem J, 2009 Apr 1. PMID 19102727.Biochemical characterization of human epidermal retinol dehydrogenase 2. Lee SA, et al. Chem Biol Interact, 2009 Mar 16. PMID 18926804.
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