RDX Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant RDX.
|Application ||WB, IF|
|Calculated MW||68564 Da|
|Other Names||Radixin, RDX|
|Target/Specificity||RDX (AAH47109, 1 a.a. ~ 583 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RDX Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses.
Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. Parisiadou L, et al. J Neurosci, 2009 Nov 4. PMID 19890007.Regulation of NK cell trafficking by CD81. Kr?mer B, et al. Eur J Immunol, 2009 Dec. PMID 19830727.Evaluation of nine candidate genes in patients with normal tension glaucoma: a case control study. Wolf C, et al. BMC Med Genet, 2009 Sep 15. PMID 19754948.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation. Belkina NV, et al. Proc Natl Acad Sci U S A, 2009 Mar 24. PMID 19255442.
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