RDX Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a full length recombinant RDX.
|Application ||WB, IF|
|Calculated MW||68564 Da|
|Other Names||Radixin, RDX|
|Target/Specificity||RDX (AAH47109, 1 a.a. ~ 583 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RDX Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses.
1.Radixin expression in microglia after cortical stroke lesion.Persson A, Osman A, Bolouri H, Mallard C, Kuhn HGGlia. 2013 Feb 26. doi: 10.1002/glia.22473.2.Molecular architecture of the chick vestibular hair bundle.Shin JB, Krey JF, Hassan A, Metlagel Z, Tauscher AN, Pagana JM, Sherman NE, Jeffery ED, Spinelli KJ, Zhao H, Wilmarth PA, Choi D, David LL, Auer M, Barr-Gillespie PG.Nat Neurosci. 2013 Jan 20. doi: 10.1038/nn.3312.3.Large membrane domains in hair bundles specify spatially constricted radixin activation.Zhao H, Williams DE, Shin JB, Brugger B, Gillespie PG.J Neurosci. 2012 Mar 28;32(13):4600-9.
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