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REPS2 Antibody (monoclonal) (M01A)

Mouse monoclonal antibody raised against a partial recombinant REPS2.

  • WB - REPS2 Antibody (monoclonal) (M01A) AT3618a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - REPS2 Antibody (monoclonal) (M01A) AT3618a
    REPS2 monoclonal antibody (M01A), clone 4C2 Western Blot analysis of REPS2 expression in NIH/3T3 ( (Cat # AT3618a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NFH8
Other Accession NM_004726
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgM Kappa
Clone Names 4C2
Calculated MW 71534 Da
Additional Information
Gene ID 9185
Other Names RalBP1-associated Eps domain-containing protein 2, Partner of RalBP1, RalBP1-interacting protein 2, REPS2, POB1
Target/Specificity REPS2 (NP_004717, 66 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsREPS2 Antibody (monoclonal) (M01A) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.


TMEM25, REPS2 and Meis 1: favourable prognostic and predictive biomarkers for breast cancer. Doolan P, et al. Tumour Biol, 2009. PMID 19776672.Hsf-1 and POB1 induce drug sensitivity and apoptosis by inhibiting Ralbp1. Singhal SS, et al. J Biol Chem, 2008 Jul 11. PMID 18474607.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.POB1 over-expression inhibits RLIP76-mediated transport of glutathione-conjugates, drugs and promotes apoptosis. Yadav S, et al. Biochem Biophys Res Commun, 2005 Mar 25. PMID 15707977.EGF signalling in prostate cancer cell lines is inhibited by a high expression level of the endocytosis protein REPS2. Oosterhoff JK, et al. Int J Cancer, 2005 Feb 10. PMID 15455380.

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$ 315.00
Cat# AT3618a
(40 western blots)
Availability: 7-10 days
Bulk Size
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