RGL2 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant RGL2.
|Application ||WB, IF, E|
|Calculated MW||83549 Da|
|Other Names||Ral guanine nucleotide dissociation stimulator-like 2, RalGDS-like 2, RalGDS-like factor, Ras-associated protein RAB2L, RGL2, RAB2L|
|Target/Specificity||RGL2 (AAH32681, 644 a.a. ~ 743 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RGL2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1.M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells.Castro AF, Campos T, Babcock JT, Armijo ME, Martinez-Conde A, Pincheira R, Quilliam LA.J Cell Biochem. 2011 Nov 17. doi: 10.1002/ jcb.23458.2.Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms.Vigil D, Martin TD, Williams F, Yeh JJ, Campbell SL, Der CJ.J Biol Chem. 2010 Nov 5;285(45):34729-40. Epub 2010 Aug 27.
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