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RGS4 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant RGS4.

  • WB - RGS4 Antibody (monoclonal) (M01) AT3631a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (48.29 KDa) .
  • WB - RGS4 Antibody (monoclonal) (M01) AT3631a
    Western Blot analysis of RGS4 expression in transfected 293T cell line by RGS4 monoclonal antibody (M01), clone 2B2.

    Lane 1: RGS4 transfected lysate(23.3 KDa).
    Lane 2: Non-transfected lysate.
  • E - RGS4 Antibody (monoclonal) (M01) AT3631a
    Detection limit for recombinant GST tagged RGS4 is 0.1 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49798
Other Accession BC051869
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 2B2
Calculated MW 23256 Da
Additional Information
Gene ID 5999
Other Names Regulator of G-protein signaling 4, RGP4, RGS4, RGS4
Target/Specificity RGS4 (AAH51869, 1 a.a. ~ 205 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsRGS4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Genetic Variations in Regulator of G-Protein Signaling Genes as Susceptibility Loci for Second Primary Tumor/Recurrence in Head and Neck Squamous Cell Carcinoma. Wang J, et al. Carcinogenesis, 2010 Jul 12. PMID 20627871.Association of polymorphisms in RGS4 and expression of RGS transcripts in the brains of human alcoholics. Ho AM, et al. Brain Res, 2010 Jun 22. PMID 20430014.Association study between RGS4 and bipolar disorder in the Chinese Han population. Li Y, et al. Psychiatr Genet, 2010 Jun. PMID 20414142.Association study of NRG1, DTNBP1, RGS4, G72/G30, and PIP5K2A with schizophrenia and symptom severity in a Hungarian sample. R?thelyi JM, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Apr 5. PMID 19937977.

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$ 315.00
Cat# AT3631a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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