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RIOK3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant RIOK3.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP, E |
|---|---|
| Primary Accession | O14730 |
| Other Accession | BC039729 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 4A12-1D2 |
| Calculated MW | 59093 Da |
| Gene ID | 8780 |
|---|---|
| Other Names | Serine/threonine-protein kinase RIO3, RIO kinase 3, sudD homolog, RIOK3, SUDD |
| Target/Specificity | RIOK3 (AAH39729, 1 a.a. ~ 516 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RIOK3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The specific function of this gene has not yet been determined.
References
1.Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer.Kimmelman AC, Hezel AF, Aguirre AJ, Zheng H, Paik JH, Ying H, Chu GC, Zhang JX, Sahin E, Yeo G, Ponugoti A, Nabioullin R, Deroo S, Yang S, Wang X, McGrath JP, Protopopova M, Ivanova E, Zhang J, Feng B, Tsao MS, Redston M, Protopopov A, Xiao Y, Futreal PA,Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19372-7. Epub 2008 Dec 2.
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