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RLN1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant RLN1.

  • WB - RLN1 Antibody (monoclonal) (M01) AT3651a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (43.12 KDa) .
  • IP - RLN1 Antibody (monoclonal) (M01) AT3651a
    Immunoprecipitation of RLN1 transfected lysate using anti-RLN1 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with RLN1 MaxPab rabbit polyclonal antibody.
  • E - RLN1 Antibody (monoclonal) (M01) AT3651a
    Detection limit for recombinant GST tagged RLN1 is approximately 10ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04808
Other Accession BC005956
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1H6
Calculated MW 21146 Da
Additional Information
Gene ID 6013
Other Names Prorelaxin H1, Relaxin B chain, Relaxin A chain, RLN1
Target/Specificity RLN1 (AAH05956.1, 27 a.a. ~ 185 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsRLN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.


Relaxin enhances S100A4 and promotes growth of human thyroid carcinoma cell xenografts. Radestock Y, et al. Mol Cancer Res, 2010 Apr. PMID 20332215.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Polymorphisms in the promoter region of relaxin-2 and preterm birth: involvement of relaxin in the etiology of preterm birth. Vogel I, et al. In Vivo, 2009 Nov-Dec. PMID 20023247.Relaxin stimulates osteoclast differentiation and activation. Ferlin A, et al. Bone, 2010 Feb. PMID 19833242.Serum relaxin levels are reduced in pregnant women with a history of recurrent miscarriage, and correlate with maternal uterine artery Doppler indices in first trimester. Anumba DO, et al. Eur J Obstet Gynecol Reprod Biol, 2009 Nov. PMID 19695764.

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$ 315.00
Cat# AT3651a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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