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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   RNF125 Antibody (monoclonal) (M01)   

RNF125 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant RNF125.

  • WB - RNF125 Antibody (monoclonal) (M01) AT3661a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.53 KDa) .
  • E - RNF125 Antibody (monoclonal) (M01) AT3661a
    Detection limit for recombinant GST tagged RNF125 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96EQ8
Other Accession NM_017831
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1A5
Calculated MW 26454 Da
Additional Information
Gene ID 54941
Other Names E3 ubiquitin-protein ligase RNF125, 632-, RING finger protein 125, T-cell RING activation protein 1, TRAC-1, RNF125
Target/Specificity RNF125 (NP_060301, 143 a.a. ~ 231 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsRNF125 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a novel E3 ubiquitin ligase that contains an N-terminal RING finger domain. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.


T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain. Giannini AL, et al. Biochem J, 2008 Feb 15. PMID 17990982.UbcH8 regulates ubiquitin and ISG15 conjugation to RIG-I. Arimoto K, et al. Mol Immunol, 2008 Feb. PMID 17719635.The RING finger ubiquitin ligase RNF125/TRAC-1 down-modulates HIV-1 replication in primary human peripheral blood mononuclear cells. Shoji-Kawata S, et al. Virology, 2007 Nov 10. PMID 17643463.A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation. Zhao H, et al. J Immunol, 2005 May 1. PMID 15843525.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

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$ 315.00
Cat# AT3661a
(40 western blots)
Availability: 7-10 days
Bulk Size
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