RNF141 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RNF141.
|Application ||WB, IHC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||25535 Da|
|Other Names||RING finger protein 141, Zinc finger protein 230, RNF141, ZNF230|
|Target/Specificity||RNF141 (NP_001008563, 141 a.a. ~ 229 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RNF141 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients. Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis.
High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles M, et al. Science, 2005 Mar 11. PMID 15761153.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Molecular cloning and characterization of a mouse spermatogenesis-related ring finger gene znf230. Qiu W, et al. Biochem Biophys Res Commun, 2003 Jun 27. PMID 12804569.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.The shorter zinc finger protein ZNF230 gene message is transcribed in fertile male testes and may be related to human spermatogenesis. Zhang S, et al. Biochem J, 2001 Nov 1. PMID 11672448.
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