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>   home   >   Products   >   Primary Antibodies   >   RNUT1 Antibody (monoclonal) (M01)   

RNUT1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant RNUT1.

  • WB - RNUT1 Antibody (monoclonal) (M01) AT3683a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (65.34 KDa) .
  • WB - RNUT1 Antibody (monoclonal) (M01) AT3683a
    RNUT1 monoclonal antibody (M01), clone 2B2-1B4 Western Blot analysis of RNUT1 expression in Jurkat ( (Cat # AT3683a )
  • IF - RNUT1 Antibody (monoclonal) (M01) AT3683a
    Immunofluorescence of monoclonal antibody to RNUT1 on HeLa cell. [antibody concentration 10 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95149
Other Accession BC004203
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a kappa
Clone Names 2B2-1B4
Calculated MW 41143 Da
Additional Information
Gene ID 10073
Other Names Snurportin-1, RNA U transporter 1, SNUPN, RNUT1, SPN1
Target/Specificity RNUT1 (AAH04203, 1 a.a. ~ 360 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsRNUT1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.


Molecular determinants of snurportin 1 ligand affinity and structural response upon binding. Goette M, et al. Biophys J, 2009 Jul 22. PMID 19619473.Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP. Monecke T, et al. Science, 2009 May 22. PMID 19389996.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.Cross-talk between snurportin1 subdomains. Ospina JK, et al. Mol Biol Cell, 2005 Oct. PMID 16030253.Structural basis for m3G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1. Strasser A, et al. EMBO J, 2005 Jul 6. PMID 15920472.

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$ 315.00
Cat# AT3683a
(40 western blots)
Availability: 7-10 days
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