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ROBO2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ROBO2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HCK4 |
| Other Accession | NM_002942 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 4G5 |
| Calculated MW | 151200 Da |
| Gene ID | 6092 |
|---|---|
| Other Names | Roundabout homolog 2, ROBO2, KIAA1568 |
| Target/Specificity | ROBO2 (NP_002933, 441 a.a. ~ 540 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ROBO2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.In search of genes associated with risk for psychopathic tendencies in children: a two-stage genome-wide association study of pooled DNA. Viding E, et al. J Child Psychol Psychiatry, 2010 Jul. PMID 20345837.Human variation in alcohol response is influenced by variation in neuronal signaling genes. Joslyn G, et al. Alcohol Clin Exp Res, 2010 May. PMID 20201926.Association of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters. Sokolowski M, et al. Mol Psychiatry, 2010 Jan. PMID 20029409.Whole-genome linkage and association scan in primary, nonsyndromic vesicoureteric reflux. Cordell HJ, et al. J Am Soc Nephrol, 2010 Jan. PMID 19959718.
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