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RP13-297E16.1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant RP13-297E16.1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q02040 |
| Other Accession | NM_005088 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 2G8 |
| Calculated MW | 80735 Da |
| Gene ID | 8227 |
|---|---|
| Other Names | A-kinase anchor protein 17A, AKAP-17A, 721P, B-lymphocyte antigen, Protein XE7, Protein kinase A-anchoring protein 17A, PRKA17A, Splicing factor, arginine/serine-rich 17A, AKAP17A, CXYorf3, DXYS155E, SFRS17A, XE7 |
| Target/Specificity | SFRS17A (NP_005079, 53 a.a. ~ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RP13-297E16.1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.
References
Splicing factor arginine/serine-rich 17A (SFRS17A) is an A-kinase anchoring protein that targets protein kinase A to splicing factor compartments. Jarnaess E, et al. J Biol Chem, 2009 Dec 11. PMID 19840947.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265. Mangs AH, et al. Nucleic Acids Res, 2006. PMID 16982639.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.
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