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RTN2 Antibody (monoclonal) (M05)

Mouse monoclonal antibody raised against a partial recombinant RTN2.

     
  • WB - RTN2 Antibody (monoclonal) (M05) AT3734a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
    detail
  • WB - RTN2 Antibody (monoclonal) (M05) AT3734a
    Western Blot analysis of RTN2 expression in transfected 293T cell line by RTN2 monoclonal antibody (M05), clone 6A11.

    Lane 1: RTN2 transfected lysate(59.264 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O75298
Other Accession NM_005619
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 6A11
Calculated MW 59264 Da
Additional Information
Gene ID 6253
Other Names Reticulon-2, Neuroendocrine-specific protein-like 1, NSP-like protein 1, Neuroendocrine-specific protein-like I, NSP-like protein I, NSPLI, RTN2, NSPL1
Target/Specificity RTN2 (NP_005610, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsRTN2 Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

References

Functional role of neuroendocrine-specific protein-like 1 in membrane translocation of GLUT4. Ikemoto T, et al. Diabetes, 2009 Dec. PMID 19720795.Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1. Liu Y, et al. J Biol Chem, 2008 Mar 7. PMID 18096700.Phosphoproteomic analysis of the developing mouse brain. Ballif BA, et al. Mol Cell Proteomics, 2004 Nov. PMID 15345747.Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation. He W, et al. Nat Med, 2004 Sep. PMID 15286784.Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport. Reuter TY, et al. Exp Cell Res, 2003 Oct 1. PMID 14499622.

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$ 350.00
Cat# AT3734a
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