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SAV1 Antibody (monoclonal) (M02)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT3774a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
SAV1 Antibody (monoclonal) (M02) - Product info | |
| Application | IF, WB
|
| Primary Accession | Q9H4B6 |
| Other Accession | NP_068590 |
| Reactivity | Human |
| Isotype | IgG2a Kappa |
| Clone Names | 3B2 |
| Calculated MW | 44634 Da |
SAV1 Antibody (monoclonal) (M02) - Additional info | |
| Gene ID 60485 | |
| Other Names SAV, WW45, WWP4, salvadorsalvador homolog 1 (Drosophila) | |
| Target/Specificity SAV1 (NP_068590, 300 a.a. ~ 384 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions SAV1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. | |
SAV1 Antibody (monoclonal) (M02) - Related products
DC04899: Human SAV1 cDNA Clone
SAV1 Antibody (monoclonal) (M02) - Application data
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Immunofluorescence of monoclonal antibody to SAV1 (AT3774a) on HeLa cell . [antibody concentration 60 ug/ml]
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SAV1 monoclonal antibody (M02), clone 3B2 Western Blot analysis of SAV1 expression in Hela NE ( Cat # L013V3 ).
SAV1 Antibody (monoclonal) (M02) - Research Areas
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BACKGROUND
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a coiled-coil region. It is ubiquitously expressed in adult tissues. The encoded protein is 94% identical to the mouse protein at the amino acid level.
REFERENCES
The human WW45 protein enhances MST1-mediated apoptosis in vivo. Luo X, et al. Int J Mol Med, 2009 Mar. PMID 19212654. Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation. Callus BA, et al. FEBS J, 2006 Sep. PMID 16930133. Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. Benzinger A, et al. Mol Cell Proteomics, 2005 Jun. PMID 15778465. The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Chan EH, et al. Oncogene, 2005 Mar 17. PMID 15688006. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
