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SCARB2 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT3784a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
SCARB2 Antibody (monoclonal) (M01) - Product info | |
| Primary Accession | Q14108 |
| Other Accession | NP_005497 |
| Reactivity | Human |
| Isotype | IgG2a Kappa |
| Clone Names | 1C8 |
| Calculated MW | 54290 Da |
SCARB2 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 950 | |
| Other Names CD36L2, HLGP85, LIMPII, SRBIIscavenger receptor class B, member 2 | |
| Target/Specificity SCARB2 (NP_005497, 339 a.a. ~ 438 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions SCARB2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
SCARB2 Antibody (monoclonal) (M01) - Application data
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Detection limit for recombinant GST tagged SCARB2 is approximately 0.1ng/ml as a capture antibody.
SCARB2 Antibody (monoclonal) (M01) - Related products
RI14712: SCARB2 predesign siRNA
DC05144: Human SCARB2 cDNA Clone
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BACKGROUND
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Studies of the similar protein in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. Deficiency of the similar protein in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Rua?o G, et al. Pharmacogenomics, 2010 Jul. PMID 20602615.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Distribution of smooth muscle cells and macrophages expressing scavenger receptor BI/II in atherosclerosis. Ishikawa Y, et al. J Atheroscler Thromb, 2009. PMID 20032583.Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand beta-glucocerebrosidase. Blanz J, et al. Hum Mol Genet, 2010 Feb 15. PMID 19933215.
